Saturday, August 29, 2015


January 5, 2016

                                        OPEN LETTER:  "Their Secret Cause of Autism"

Public Comment Submission- To: HHS OARC and IACC Committee on Autism Spectrum Disorder

Purpose-  Increasing Evidence Reveals A Most Probable Cause Of Autism Worthy Of Lawful Public Disclosure, Until Proven As Neuro-developmentally Safe.

From-  Investigative Researcher G. A. Elbek

Dear OARC, and IACC Committee Members,

As an investigative researcher into the cause of autism, I very much appreciate your due diligence to review this public comment related to the epidemic of Autism Spectrum Disorder.  I request that the following factual information be seriously focused upon and dutifully reviewed, without bias, by responsible and respectable IACC Committee members.    

It is well-known that fetal, infant, and child brain development is a most delicate and critical time-frame that largely relies upon the successful assembly of hard wired brain cells, brain systems, and brain circuitry of which must NOT under any circumstances be breached.  Unquestionably, it is overwhelmingly research study established that interruptions in multiple developing brain systems are caused by accidental fetal, infant, and/or child exposure(s) to poisonous environmental estrogenic hormone disruptors with resulting severe and irreversible developmental adverse brain effects such as behavioral disorders to include autism.

Baby formulas, the most critical nutritional food source to advance life-saving developmental health are not FDA approved.  However, prior to U.S. marketing on grocer shelves, highly profitable infant formula manufacturers are FDA required to first prove their infant formulas are: 1. Safe, and 2. Support developmental growth.  Slipping through multiple regulatory health requirements, infant formulas made from soybeans became U.S. marketed without established proof of either of those.  

National Institute of Health, (NIH), National Institute of Environmental Health Sciences, (NIEHS) includes; "Soy Infant Formula" on their poisonous list of "Environmental Agents.”  This NIH NIEHS toxic list reads,  “Environmental Agents- Air Pollution, Allergens, Arsenic, Dioxins, Endocrine Disruptors, Formaldehyde, Lead, Mercury, Mold, Pesticides, Radon, Soy Infant Formula, Styrene, and Water Pollution."
While each of the above are confirmed estrogenic hormone disruptors, it is only one, “Soy Infant Formulas” that contain developmentally toxic phytoestrogenic hormone disruptors that are withheld from an innocent and trusting American public. Which of the above NIH NIEHS confirmed brain-toxic “Environmental Agents,” will you choose to place into the mouth of your baby, or your grandbaby all day and night for the long-term…arsenic, dioxins, lead, mold…or Soy Infant Formula?  

As equal to ALL developmentally poisonous estrogenic endocrine disruptors, NEVER are the unknown fluctuating dosage levels of several soybean phytoestrogenic endocrine disruptors: genistein, daidzein, glycitein, and the unknown number of people who metabolize daidzein to highly potent equol, proven as developmentally body- or brain-safe. 

1999, FDA Federal Register confirms, "GRAS status of soy did not include a thorough evaluation of the safety of potentially harmful components, e.g. lysioalanine, nitrites and nitrosamines, trypsin inhibitors, phytates and isoflavones.  Trypsin inhibitors are responsible for hyperplasia and formation of (pancreatic) nodules seen in animal studies.  Further...high levels of trypsin inhibitors in humans can evoke this mechanism." 

As fact, there is no established fetal, infant, or child soybean benefit: no nutritional value, no evidence of safety, or survival.  As fact, soybeans contain unknown fluctuating dosage levels of a multitude of toxic fetal, infant, and child brain-poisons to include: 1. Several toxic soy phytoestrogenic endocrine disruptors   2. Highest food-toxic levels of Phytic Acid- block the absorption of essential developmental minerals i.e., calcium, magnesium iron, zinc.  3. Toxic Trypsin Inhibitors- that inhibit digestion and absorption of nutrients, and proven to prevent normal growth also involving the brain and nervous system.  4. Inhibits topoisomerase- an essential enzyme involved in DNA replication, (studies also report as a cause of childhood leukemia).  5. Multiple dangerous heavy metals (in detail below).  6. Additional soybean phyto-brain poisons- lysioalanine, nitrites, nitrosamines… and more! 

Also without evidence of developmental brain-safety additional poisons are added to soy infant formulas, such as dangerously high levels of: GMO Soy, Corn Syrup- 40.8 -55%, GMO Corn, and Sugar- 10.2-11%! 

And corn syrup is processed through reagents that are generated by chloralkalide plants.  Chloralkalide plants use a mercury cell process in which laboratories have identified levels of mercury within high-fructose corn syrupAdd mercury to the growing list of soy phyto-poisonous developmental neuro-toxicants.

Never proven as developmentally safe: Innumerable soybean plant-poisons placed into soy infant formulas, soy-contaminated infant “milk” formulas and foods are repeatedly and increasingly NIH Pubmed study concluded as deleterious to fetal, infant, and child physiological, reproductive, and neurological health, thus defining “adulterated” food.  (21 U.S. Code 342).

Never proven as developmentally safe: Soybean product labels neglect mention of  toxic chemical contents of these several soy phytoestrogenic endocrine disruptors plus additional soybean poisons that are established developmental body- and brain-poisonous, thus defining “misbranded.”

Following are renowned NIH, FDA, U.S., and worldwide scientifically researched publish studies, as well as U.S. Health Official testimonials of which repeatedly and increasingly conclude that fetal, infant, and/or child exposure to the innumerable soybean phyto-poisons have established capabilities to severely disrupt, and irreversibly damage several developmental brain systems that are directly related to the cause of autism. 

This is an urgent request that you, the U.S. appointed IACC Committee will righteously, responsibly, equally, and lawfully alert a trusting American public, and loving parents, to the following overwhelming accumulative evidence that proves soy phytoestrogenic endocrine disruptors plus additional soy phyto-poisons as a possible, probable, and absolute cause of multiple fetal, infant, and child adverse behavioral effects, to include autism, until otherwise proven as developmentally brain-safe.


NIH NIEHS reports, "Why are people concerned about soy infant formula? The safety of soy infant formula has been debated because it typically contains a class of compounds called isoflavones.  These isoflavones are referred to as phytoestrogens because they are found in plants (phyto) and because of their ability to act like the hormone estrogen in the body.  ...infants are more likely than adults to be vulnerable to the estrogen-like effects of the phytoestrogens in soy. is recognized that infants go through developmental stages that are sensitive to estrogens.  Therefore, infants are more likely than adults to be vulnerable to the estrogen-like effects of the phytoestrogens in soy.  In some cases, the health effects resulting from a soy-based diet may not be apparent until years later.”

2013, "Soy Infant Formula may be Associated with Autistic Behaviors," CJ Westmark confirms, "Medical record data were analyzed from Simons Foundation Autism Research Initiative Simplex Collection....  This study provides preliminary data that the use of soy-based infant formula may be associated with specific autistic behaviors."

Nearly a thousand NIH Pubmed published studies concur with this 2010, Bar-El DS and R. Reifen report, “Soy as an endocrine disruptor: cause for caution? Endocrine disrupting compounds (EDCs) alter the function of the endocrine system and consequently cause adverse health effects.  Phytoestrogens, natural plant compounds abundantly found in soy and soy products, behave as weak estrogen mimics or as antiestrogens.”   Journal of Pediatric Endocrinology and Metabolism. 2010 Sep:23(9) 855-861.

2009, Water Environment Research Foundation (WERF) reports, “Study Contaminates, (or emerging contaminates) of Endocrine Disrupting Chemicals.  The classes of EDC included: steroids/sterols naturally occurring synthetic; phytoestrogens….   The term ‘emerging contaminates’ refers broadly to those synthetic or naturally occurring chemicals,… that have not been commonly monitored in the environment but which are increasing concern because of their known or suspected adverse ecological or human health effects.”

Throughout prior decades and to present day, NIH researchers consistently report as the following to the FDA.  This time it is renowned NIH soy researchers Sheehan and Doerge who back in 1999 report,  “Subsequently, this same group showed a significant dose-dependent risk (up to 2.4 fold) for development of vascular dementia and brain atrophy from consumption of tofu, a soy product rich in isoflavones (White, et al., 1996b). This finding is consistent with the environmental causation suggested from the earlier analysis, and provides evidence that soy (tofu) phytoestrogens causes vascular dementia.”

Without HHS, NIH, or FDA established evidence of fetal, infant, and child soy phyto-toxic safety, it must be equally understood by all American people that soybean phytoestrogenic endocrine disruptors and additional multiple soybean phyto-poisons are severe and irreversible developmental body- and brain-poisons.  What causes dementia in adult men can cause brain disorders, to include autism, in exposed fetus, infants, and children, until proven otherwise, until ever proven as developmentally body- and brain-safe…which in fact, has never been done! 

2002, “Global Assessment of the State-of-the-Science of Endocrine Disruptors,” is an expert document prepared on behalf of World Health Organization (WHO) that states,  “‘In this document, Endocrine Disrupting Chemicals (EDCs) have been defined as exogenous substances that alter function(s) of the endocrine system and consequently cause adverse health effects in an intact organism, or its progeny, or (sub) populations.’ The diversity of chemicals includes natural and synthetic hormones, phytoestrogens, pesticides, and a variety of industrial chemicals and by-products. The ubiquitous presence of natural hormones and plant estrogens poses difficult analytical issues because these natural EDCs may be more potent than environmental EDCs.  One of the most important issues that complicate assessing exposure to EDCs in both wildlife and humans is the level, timing, and duration of exposure relative to the developmental stage of the organism. Exposure during fixed time frames in development when programming of the endocrine system is occurring may result in permanent changes...”

In regards to developmental exposure to soy phytoestrogens the World Health Organization expresses, Major concern.

U.S. Health Official Adverse Soy Testimonials:

1.  2010 NIH NIMH Deputy Director Ms. Daniels states, "Dr. Insel, (former IACC Director) is aware of the endocrine disrupting properties of soy, as he has personally done research in this area....  Soy may indeed be one of many environmental factors that contributes to various disorders and deserves further study."

2.  2015, NIH NIEHS Officer of Communications, Ian Thomas confirms, "...our scientists study things in the environment that could potentially make people sickThis might include chemical agents like formaldehyde and pesticides or natural agents like mold and arsenic.  This also includes the study of soy."

3.  NTP NIEHS Director Linda Birnbaum reports, “We know that young children are especially vulnerable to adverse health consequences of a wide variety of environmental exposures.  …the active growth of children’s organs and tissues enhances their susceptibility to environmental damage….   We also know much more about the linkages between environmental exposures and specific diseases and dysfunctions- not just childhood diseases, but effects of prenatal and childhood exposures can show up years later for example, as reproductive problems or cancer.  The neurological and cognitive development of children is especially vulnerable to some environmental effects.  A major area of study is the role of chemicals in the environment, with a primary focus on hormonally active agents (endocrine disruptors).  The types of chemicals measured include…phytoestrogens found in foods….   Soy formula use is common, and there is public health concern about its effects on infants and young children.  Other NIEHS programs are also looking at soy formula.  Soy-fed infants have much higher exposure to endocrine-active compounds in their diets….   Soy-fed infants may be the group with the highest exposure to any environmental estrogen.  Normal endocrine signaling involves very small changes in hormone levels, yet these changes can have significant biological effects.  That means subtle disruptions of endocrine signaling is a plausible mechanism by which chemical exposures at low doses can have effects on the body.  Endocrine signaling governs virtually every organ and process in the body.   …effects of exposure to endocrine disruptors can be observed long after the actual exposure has ceased.  This is especially true for growth and development, processes that are very sensitive to endocrine regulation. ”, and /2010/02/t20100225a.html

4.  2008, FDA, Center for Food Safety and Applied Nutrition (CFSAN) Deputy Director Janice Oliver reports, "FDA acknowledges that "concerns" have been voiced about possible effects of isoflavones in soy infant formulas on sexual development, neurobehavioral development, immune function, and thyroid disease."  

5.  FDA includes soybeans on their “Poisonous Plant Database” stating- "Phytoestrogens: toxicants of plant origin."  The FDA Poisonous Plant Database also includes hundreds of studies reporting adverse developmental soybean phyto-poisonous effects. 

6.  2015, NTP Senior Scientist, John Bucher reports, "The larger issue of just how significant exposures to potential (soy) endocrine disruptors are to public health is still a subject of intensive research.  To date it appears that exposure to the developing fetus are more potentially harmful than those after birth."

7.  In-depth history of MedWatch, and CAERS (CFSAN “Adverse Events Reporting System”)- reports are flooded with alarmingly numbers of guilt-ridden parents in despair as they detail a variety of adverse health effects caused to their soy-exposed child(ren), while without public disclosure!

8.  1997and revised in 2013, The (U.S.) Endocrine Society reports, "We conclude that (soy) phytoestrogens exhibit physiological effects in humans." 

9.  Toxic transplacental or fetal contamination caused from maternal exposure to endocrine disruptors such as: alcohol, plastics, pesticides, pollution, etc., all carry legitimate "Warning" labels during pregnancy, with the ONE exception being soy!  Transplacental transfer of poisonous soy phytoestrogenic endocrine disruptors carry no law-abiding “Warning” labels!   Why Not?

10.  2000, EPA “Final Report: Developmental Effects of  Soy Phytoestrogens,” (Project period, 1996- 1999)- “However, an increase of soy consumption in the North American diet has resulted in increased exposure to dietary estrogen mimics by reproductive-aged women raising concern regarding possible effects on the fetus and neonate.”

AUTISM-  Multiple Soybean Phyto-Poisons Are Proven To Cause Multiple Adverse Neurological Effects Directly Related to the Cause of Autism:

It is critical that the developing brain is formed though a most intricate genetic blueprint of balanced hormones, essential minerals and nutrients that must not be disrupted or dismantled.  Never proven as brain-safe, several hundred times over and over again, soy phytoestrogenic endocrine disruptors plus additional soybean phyto-poisons are NIH Pubmed study concluded to dangerously disrupt, dismantle, and destroy multiple developing brain systems that are directly related to adverse brain development and the cause of brain disorders to include autism.  There is no evidence proving a child’s brain is able to survive soy phyto-poisonous exposure(s):

How are the unknown, fluctuating dosage levels of soybean phytoestrogenic endocrine disruptors plus additional soybean phyto-poisons related to the fetal, infant, and/or child cause of autism?  Innumerable studies, largely NIH Pubmed published studies, repeatedly and increasingly conclude: 

1. Autism is caused by an imbalance of excitatory and inhibitory neurotransmitters- Soy phyto-poisons are the study concluded cause.  2. Autism is caused by oxidative stress and metabolic perturbations- Soy phyto-poisons are the study concluded cause.  3. Autism is caused by environmental perturbations- Soy phyto-poisons are the study concluded cause.  4. Autism is caused by interruptions in neural pathways- Soy phyto-poisons are the study concluded cause.  5. Autism is associated with additional physiological conditions: gastrointestinal distress, immune deficiency disorders, thyroid dysfunction- Soy phyto-poisons are the study concluded cause.  6. Autism is caused by  gene disrupting mutations- Soy phyto-poisons are the study concluded cause.  7. Autism is caused by mitrochondrial dysfunction-  Soy phyto-poisons are the study concluded cause.  8. Autism is caused by heavy metal poisoning- Soy phyto-poisons are the study concluded cause.  9. Autism is caused by inhibition of tyrosine kinase MET gene signaling- Soy phyto-poisons are the study concluded cause.  10.  Autism is caused by inhibition of RET receptor- Soy phyto-poisons are the study concluded cause.  11.  Autism is caused by methionine deficiency- Soy phyto-poisons are the study concluded cause. 12. Autism is caused by inhibition of tryptophan deficiency- Soy phyto-poisons are the study concluded cause.  13.  Autism is caused by inhibition of astrocytes neuroglial cells- Soy phyto-poisons are the study concluded cause. 14. Autism is caused by Fragile X syndrome, Soy phyto-poisons are the study concluded cause!

* Autism is caused by fetal, infant, and/or child disruption in neurotransmitter systems. Soy phytoestrogenic endocrine disruptors are repeatedly NIH Pubmed study concluded to dangerously interfere and manipulate several neurotransmitters: vasopressin, oxytocin, serotonin, dopamine, GABA, glutamate, and cholinergic!

*  Autism is caused by essential mineral imbalance-  Soybean heavy metals and/or phytic acid are study reported to cause: zinc deficiency, iodine deficiency, calcium overdose, calbindin D28k overdose, iron deficiency, copper deficiency, thiamin (B1) deficiency, selenium overdose, phosphorus overdose, magnesium deficiency or manganese overdose. 

* Autism is caused by fragile X syndrome- Soy phytoestrogens are NIH Pubmed study reported to increase the risk of Fragile X syndrome that affects the Fragile X mental retardation gene on the X chromosome that results in failure to express the fragile X mental retardation protein which is required for normal neural development.

* Autism is caused by heavy metal contamination- Soybeans are NIH Pubmed study confirmed cause heavy mental contamination: aluminum contamination, cadmium contamination, thallium contamination, and lead contamination.  Increasing soybean lead levels are also reportedly caused by GMO soy, as most often marketed in the soybeans used in infant formulas and foods, without right-to-know labeling! 

* The Office of Environmental Health Hazard Assessment (OEHHA) website reports,  " ...manganese exposures in childhood are associated with impaired neurodevelopment including decrements in intellectual function.  Some infant formulas and foods are high in manganese. Soy formula may contain 200-300 micrograms, compared with 6 micrograms in breast milk.  High dietary soy intake can put infants at greater risk of manganese toxicity.  The newborn's brain is still developing, myelination is incomplete, and the blood-brain barrier is not fully formed. These conditions facilitate manganese uptake into the central nervous system and increase the risk of attaining toxic levels."  

* Soybeans are repeatedly NIH Pubmed study concluded to contain high levels of manganese, an established cause of adverse or impaired neurodevelopment.

* Environmental Protection Agency (EPA) reports, “Formula fed infants have been shown to absorb greater amounts of manganese than breast-fed infants.  Recent California study reported a modest increase in incidence of autism was associated with highest manganese concentrations.  Manganese concentrations were higher in soy and rice drinks, and in soy formulas, than in cow’s milk formulas.  Exposure to high concentrations of manganese exposure can be detrimental to health. The primary targets of manganese toxicity are the brain and central nervous system.  Manganese…exposure to high concentrations…was associated with permanent (brain) damage, with symptoms of impaired neurological and neuromuscular control, mental and emotional disturbances, muscle stiffness, lack of coordination, tremors, difficulties with breathing or swallowing and other neuromuscular problems.”

* With EPA confirmation of high levels of manganese in soy infant formulas, NIH NIEHS Director Birnbaum also confirms, “…manganese levels… were associated in a dose-dependent fashion with decreases in intelligence.” 
*  Soy phytoestrogens are a cause of mitochondrial deficits and multiple NIH Pubmed studies conclude:  1. Soy Phytoestrogens inhibit mitochondrial activity.  2. Mitochondria are important targets of estrogen action, soy disrupts estrogen action and mitochondrial dysfunction is a primary event in glutamate neurotoxicity  3. Soy phytoestrogen genistein can inhibit FoFI-ATPase activity in rat brain mitochondria.  4. Soy phytoestrogens interrupts ATP synthase…  5. Soy phytochemcials should be included in the examination for potential cytotoxicity.  6. Genistein a major soy isoflavone,...causes  mitochondrial deficits.  

*  HHS and NIH CHARGE (Childhood Autism Risks From Genetics and the Environment) Study at U.C. Davis, "News and Updates" reports, "Study confirms mitochondrial deficits in children with autism."   Soy phytoestrogens are repeatedly study proven to cause mitochondrial deficits.
* Soy phytoestrogens are study proven to lower the cholesterol necessary for developmental formation of brain cells.  Lowering cholesterol levels in babies is  repeatedly proven to result in adverse body and brain effects.  Kaayla T. Daniel’s book,  “The Whole Soy Story,” offers a graph exposing- After one month, the level of soy phytoestrogens in premenopausal women that cause hormonal changes- 45mg, or 0.75 mg per kg of body weight.  The FDA recommended amount of soy phytoestrogens for adults to lower cholesterol- 25mg, or 0.40mg per kg of body weight.  After just one month, babies fed soy infant formulas have toxic phytoestrogen levels that measure a most frightening: “38mg isoflavone (phytoestrogens, or 6.25 mg per kg of body weight,” which largely surpasses the FDA danger zone of low cholesterol levels, (and highly toxic phytoestrogen levels) that are proven to cause adverse developmental brain effects, to include autism.

* 2009 the Karolinska Institute reports, “A derivative of cholesterol is necessary for the formation of brain cells, according to a study from the Swedish medical university Karolinska Institutet.  The study was led by Professor Ernest Arenas and demonstrates that the formation of dopamine-producing neurons during brain development in mice is dependent on the activation of a specific receptor in the brain by an oxidised form of cholesterol called oxysterol.  Dopamine-producing nerve cells play an important part in many brain functions and processes, from motor skills to reward systems and dependency. They are also the type of cell that dies in Parkinson's disease.”

* reports- Cholesterol is needed to: Prevent Aggression, Fight Cancer, Prevent Hemorrhagic Stroke, For Longevity…prevent DNA damage associated with cellular aging, and to help fight infection.  Particularly for fetus, infants, and children cholesterol is essential for life and cholesterol-lowering drugs have over 300 adverse health effects.”

* 2014, T. Sehm et al report, "In this study we investigated the impact of (dietary) isoflavonoids on glioma morphology and function.  Genistein (soy phytoestrogen) is very effective in inducing glioma cell death, it is highly toxic for primary astrocytes.”

* Autism is caused by glioma cell death, and the poisoning of astrocytes and fetal, infant, child exposure to soy phytoestrogenic hormone disruptors is the cause.

* 2010, Sofroniew and Vinters report, "Over the past 25 years it has become clear that astrocytes are responsible for a wide variety of complex and essential functions in the healthy Central Nervous System, including primary roles in synaptic transmission and information processing by neural circuit functions."

In addition to causing adverse synaptic transmission and neural circuit functions that are related to the cause of autism, the soy phytoestrogen-cause of astrocyte toxicity via glioma cell death is also reported to cause: intestinal dysfunction, diabetes, autoimmune disease, specific tumorigenesis, diabetes, Alzheimer’s disease, and more.  Many of which are the very disorders diagnosed in autistic children. 

* Back in February 18, 1999- Renowned NIH soy experts, Drs. Sheehan and Doerge together wrote directly to the FDA stating, "...there is abundant evidence that... isoflavones found in soy... demonstrate toxicity in estrogen sensitive tissues and in the thyroid.  ....this is true for a number of species, including humans.  Development is recognized as the most sensitive life stage for estrogen toxicity because of the indisputable evidence of a very wide variety of frank malformations and serious functional deficits in experimental animals and humans. Taken together, the findings presented here are self-consistent and demonstrate that genistein and other isoflavones have adverse effects in a variety of species including humans. The health labeling of soy protein isolate for foods needs to be considered just as would the addition of any estrogen…to foods. Our conclusion... no dose is without risk..."

*  Autism- Decades of NIH Pubmed published studies repeatedly conclude soybean phyto-poisons cause severe thyroid dysfunction that cause any variety of dangerous developmental immune deficiency disorders and diseases.  Thyroid disorders are study established cause of  irreversible damage to the developmental hypothalamic-pituitary-thyroid axis that lead to brain and behavioral disorders to include autism!,,

* 2004, Renowned NIH NIEHS researchers, Chen and Rogan confirm, “Both ingestion and injection of (soy) genistein can affect development of the reproductive system, decrease thymic weight... modulate immune response, or reduce thyroid peroxidase.  This highlights the urgent need to evaluate the effects of isoflavones in soy infant formula…”

* Seizures are common in autistic children, and seizures are caused by exposure to soy phyto-poisons!  These NIH Pubmed studies report, Seizures experienced by autistic children can be triggered by soy phytoestrogenic disruptions in estrogen receptor-dependent signaling mechanisms of the brain.,

* AUTISM- A TRUE soy phyto-toxic exposure history: 1. Nine months of fetal transplacental transfer of soy phyto-poisonous contamination due to maternal soy consumption.  2. Maternal consumption of soy phyto-poisons are again repeatedly transferred to nursing baby.  3. Baby is also soy phyto-toxic infant formula fed, all day and night for the long-term!  And by age 3 this baby girl is diagnosed with autism!  And how many more children fall prey to soy phyto-poisons has never been righteously investigated with autism numbers established!

LOOK At The Following Studies Out Of Several Hundred ALARMING Soy Phyto-Poisonous Published Studies Concluding Autism Probability Due To Developmental Exposure:

Awaiting responsible U.S. public disclosure, soy phytoestrogenic endocrine disruptors plus additional developmental soybean phyto-poisons can be defined in scientific literature as “neurodevelopmental toxicants” due to capabilities to: target, attack, and irreversibly disrupt, dismantle, and permanently damage multiple developing brain systems that are related to the cause of brain disorders such as autism.
(Worth Repeating) 2013, "Soy Infant Formula may be Associated with Autistic Behaviors," CJ Westmark confirms, "Medical record data were analyzed from Simons Foundation Autism Research Initiative Simplex Collection....  This study provides preliminary data that the use of soy-based infant formula may be associated with specific autistic behaviors."

Renowned researcher C.J. Westmark also reports, “We utilized medical record data from the Simons Foundation Autism Research Initiative to assess seizure incidence in autistic children fed soy-based versus other infant formula.  There were data available for 1949 subjects (87% males).  We found a 2.6-fold increase in the incidence of febrile seizures and a 4.8-fold increase in the incidence of simple partial seizure in autistic children fed soy formula.  There was a 2.1-fold increased incidence in epilepsy.  In aggregate, these data demonstrate that a soy-based diet is associated with increased seizure incidence in …autistic children.  These data raise important questions regarding the neurological side effects of a soy-based diet during postnatal development.  We did find exploratory associations between the consumption of soy-based infant formula and several autistic behaviors…”

* 1990's Renowned soy researcher Dr. Kenneth Setchell confirms, "Because these bioactive phyto-oestrogens possess a wide range of hormonal and non-hormonal activities, it has been suggested that adverse effects may occur in infants fed soy-based formulas.  The daily exposure of infants to isoflavones in soy infant formulas is 6-11- fold higher on a body weight basis than the dose that has hormonal effects in adults consuming soy foods.  Circulating concentrations of isoflavones in the seven infants fed soy-based formula were 13,000-22,000 times higher than plasma oestradiol concentrations in early life, and may be sufficient to exert biological effects, whereas the contribution of isoflavone from breast-milk and cow-milk is negligible."

1997, renowned soy researcher Setchell et al also confirm, “In placental mammals, the fetus is continuously exposed to high levels of estrogen from the placenta and the mother.  Environmental exposure to (soy) phytoestrogens during this period is expected to disrupt the function of the natural steroid hormones.” 

2014, C. J. Westmark concludes, “Soybeans are rich in phytoestrogens, “plant estrogens’ which can be transferred to offspring through the placenta as well as maternal milk.  Soy protein is rich in a type of phytoestrogens called isoflavones, which are bioactive compounds structurally similar to the female hormone estrogen.  Isoflavones can exert biological activity by mimicking the effects of mammalian estrogen and thus disrupt the endocrine cycle.  It should be noted that infants can efficiently digest, absorb, and excrete genistein and daidzein from soy-based infant formulas. At high doses genistein and daidzein are toxic to primary neuronal cultures.”

2004, Renowned soybean researcher Setchell again confirms, "Soy-derived isoflavone are the most abundant and in many ways the most studied phytoestrogens, and phytoestrogens are known endocrine disruptors.  Daidzein can be further metabolized to the potent and abundant molecule equol....  The specific influence of dietary soy phytoestrogens on consumptive, learning and memory, and anxiety-related behaviors is identified."   http://www.ncbi.nlm.nih/gov/pumben/15454683.

Never proven as fetal or neonate safe, the EPA confirms the fact, “However, an increase of soy consumption in the North American diet has resulted in increased exposure to dietary estrogen mimics by reproductive-aged women, ‘raising concern’ regarding possible effects on the fetus, and neonate.”  

 “, National Biomonitoring Program on Phytoestrogens” confirms, “Ingested daidzein is further metabolized to…equol by intestinal bacteria.  Equol, …has estrogenic activity.  About 30% of adults can be characterized as equal producers….  The relevance of equol-producer status to potential health related effects is unclear.  Equol has more potent estrogenic activity than its precursor, daidzein.  Equol also has been shown to have anti-androgenic activity in animals.  Genistein binds ER(Estrogen Receptor) -beta with greater affinity than equol (Doerge and Sheehan, 2002).  …phytoestrogens can be present in concentrations 100 to 1000 times greater than the endogenously produced estrogens.  Soy-based infant formula can result in plasma concentrations of isoflavones in infants that are 13,000- 22,000 times higher than endogenous estrogen concentrations in infants, (Setchell et al., 1997). ”

Yet the CDC will NOT lawfully alert the American public of developmental soy phytoestrogenic poisons!  Likely because the CDC is heavily funded by Pharmaceutical soy formula profiteers!

 USDA Ag-Magazine reports, "Soy-based infant formulas contain soy protein isolate (SPI).  Isoflavones are bound to soy proteins in high amounts.  One controversial aspect of soy-based formula involves isoflavones because they're believed to act similarly to the female hormone estrogen.  Critics suggest that isoflavones in soy formula might disrupt or impair development in infants." 

Yet the USDA will NOT lawfully alert the American public of developmental soy phyto-poisons!  Likely because the USDA is heavily connected to Monsanto GMO soybean profiteers!

Beginning on page 27 of "Pros and Cons of Phytoestrogens" review the "Cons" as reported by renowned NIH soy researchers H. Patisaul and W. Jefferson:  Their in-depth developmental soy exposure report is a parental nightmare while loaded with deleterious developmental brain and body effects.  Patisaul and Jefferson report, "A possibility of increasing concern is that phytoestrogen may interfere with organizational role of estrogen in the developing brain and reproductive system.  ....manipulation of estrogen during specific critical windows of development throughout gestation and early infancy leads to a myriad of adverse health outcomes including malformations in the ovary, uterus, mammary gland and prostate, early puberty, reduced fertility, disrupted brain organization, and reproductive tract cancers."

Yet the NIH will NOT lawfully alert the American public of developmental soy phyto-poisons!  How many at the NIH have ties with the powerful U.S. Soybean industry?

Dedicated researchers at the "Academics Review" report, "When hormonal effects are undesired these compounds could well be regarded as dangerous or unhealthy.  A potential undesirable effect of (soy) phytochemicals is disturbance of brain development in the unborn child.  Remember, chemicals in the diet can promote or reduce cancer risks and can affect brain development and normal organ development in unborn children, and there is no doubt that foods such as soybeans, flaxseed and mung-beans contain such chemicals.  These effects have been known to science for 50-years but it is only relatively recently that the general public have started to hear about them. Their decisions to manage diet hormone-like chemicals should be based on their particular health circumstances, stage of life, whether they are pregnant or are breast-feeding.”
Innumerable NIH Pubmed published studies also report the same conclusions as Kalkbrenner et al,  " is now understood that environmental factors play a larger role in causing autism than previously thought..." 

Throughout decades, the NIH NIEHS has repeatedly established “Soy Infant Formula” as brain and body-contaminating to fetus, infants, and children.  And now establishing a toxic list called, "Environmental Agent" that includes “Soy Infant Formula,” because soybeans contain multiple developmentally-polluting estrogenic endocrine disruptors, (plus several additional developmental poisons).  For several prior decades and continuing to this day, multiple NIEHS researchers consistently report horrific evidence of extreme and outrageous developmental soybean body- and brain-poisoning.  But at the same time, the NIH NIEHS chooses to remain publicly mute.  Why?  Can it possibly be to save soy-industry profits, while knowingly jeopardizing the body- and brain-health of American fetus, infants and children?

"Autism and the Environment," Dr. Slotkin reports, "...there is always a critical period in which any disruption of input, positive or negative, will permanently alter (brain) function.  If you send the wrong signal, it's going to produce the wrong outcome.  It is going to teach the cell to respond incorrectly to the wrong kind of input.  It will make that change permanently.  What kinds of things will do that?  Any drug of chemical that is neuroactive...reinforcing or blocking the actions of a neurotransmitter.  ....drug abuse or therapeutic agents... environmental contaminants,... all of these can lead to misprogramming of responsiveness."

2003, Journal of Agriculture and Food Chemistry; 51, 2193-2199,  Stephen Boue et al report, “Given the significant interest in the estrogenic activity of phytoestrogens, particularly isoflavones in soybean, this study was undertaken to determine the estrogenic activity….   Phytoestrogens act through both ER (estrogen receptor)-dependent and -independent mechanisms.   By mimicking 17b-estradiol, phytoestrogens bind to estrogen receptors in different body tissues with estrogenic activities….  These data were consistent with previous data indicating isoflavones preferentially bind ERb, and transcriptional activation of phytoestrogens for both ERa and ERb was observed.  However, the effects could be significant because phytoestrogens may be present at high concentrations compared to that of endogenous estrogen.   …the isoflavones contents of different varieties, crops, and harvest years vary considerably.  Much research has been conducted on the quantitation and estrogenic activity of the isoflavone daidzein and genistein found in high concentrations in soybeans.” 
* 1998, FDA Director of National Center for Toxicological Research (NCTR) Dr. Sheehan repeatedly confirms, "These considerations suggest that much closer study in experimental animals and human populations exposed to phytoestrogen-containing products, and particularly soy-based foods is necessary.  Among human exposure, infant soy formula exposure appears to provide the highest of all phytoestrogen doses and this occurs during development, often the most sensitive life-stage for induction of toxicity."

Yet neither the FDA or NCTR will lawfully alert an innocent and trusting American public of their equal acknowledgement of developmental soy phyto-toxicity! 

* 2003, USDA reports, “Methanol extracts were prepared from soybean….  These results show that several legumes are a source of phytoestrogens with high levels of estrogenic activity.” 
As fact, since the 1950’s to present day, there are nearly one thousand NIH Pubmed published studies that consistently report developmental soy phyto-poisonous conclusions as relative to this study; 2014, Singh et al, confirms, "These results suggested that the higher dose of genistein (soy phytoestrogen) can produce several undesirable effects by affecting multiple cellular pathways."

2010, Renowned soy researchers Dinsdale and Ward confirm, "Soy isoflavone are phytoestrogens with potential hormonal activity due to their similar chemical structure to 17B-estradiol.  While much of this research has focused on adult populations, infants fed soy protein based infant formula are exposed to substantial levels of soy-based foods.  Infant exposure, through soy formula primarily occurs from birth to one year of life, a stage of development that is particularly sensitive to dietary and environmental compounds."

Although Illinois is the #1 U.S. State (out of 33 States) that largely profits from soybean production, in 2010 a study from University of Illinois, Urbana concludes, "Soy-based infant formulas... contain high levels of the estrogenic isoflavone genistein leading to 'concern' that neonatal genistein exposure could cause acute and/or long-term adverse effects on reproductive and other organs.  The immediate and long-term effects in this neonatal animal model raises 'concerns' that high serum concentrations of genistein are estrogenic and could potentially impact the development of human infants fed soy formula."

2015, NIH, National Center for Complimentary and Integrative Health (NCCIH) reports, "Side Effects and Cautions- The safety of long-term use of soy isoflavones has not been established.  Until more is known about soy's effect on estrogen levels, women... who are at an increased risk for developing breast cancer, or other hormone-sensitive conditions should be particularly careful about using soy....  Minor stomach and bowel problems such as nausea, bloating and constipation are possible.  Allergic reactions such as breathing problems and rash can occur..."

That the NIH, NICCIH, also admits that the safety of soy isoflavone estrogenic endocrine disruptors “has NOT been established,” while at the same time allowing an enormous population of trusting and loving American parents to participate in this undisclosed and undocumented fetal, infant, and child soy-poisoning U.S. experiment seems nothing less than HHS, NIH, and FDA criminal! 

Louisa Barkla, Communications and Resources Officer, UNICEF UK Baby Friendly Initiative, reports, "Soya formula is made from soya, not cow’s milk.  Soya formula contains high levels of a chemical called phytoestrogen which may have negative effects on babies and so should only be used in exceptional circumstances and only under the recommendation of a doctor."

2013, “  National Biomonitoring Program- Phytoestrogens” reports, “Diet is the source of human exposure to phytoestrogens.  The absorption and metabolism of phytoestrogens demonstrate large interindividual variability.   After hydrolysis to the aglycone forms, phytoestrogens can weakly bind to estrogen-beta receptors which are expressed in arteries and smooth muscle.  Individual phytoestrogens may be either estrogen agonists or antagonists.  Numerous studies of either dietary soy or phytoestrogens and health outcomes have demonstrated inconsistent or inconclusive results.  Results of chronic feeding studies in pregnant animals suggest that high doses of phytoestrogens alter the fetal hormonal environment (Cornwell et al., 2004).”   

2000 the EPA “Final Report” confirms, “There is widespread concern that developmental exposure to endocrine active chemicals (EACs) may adversely affect reproductive, neurobehavioral, and immunological development or predispose those towards various cancers later in life.  For some of these endpoints, (soy) daidzein and genistein mimicked DES; however, unique or opposite responses were also evidence for each of the phytoestrogens, including low dose of genistein.  The window of exposure also was important for type of response elicited by the treatments; that is, in utero and lactational exposure often had different effects.  Altered outcomes… indicated that treatment effects continued to be evident after the end of the exposure window (birth or weaning).  Therefore, exposure of human fetus, and/or nursing baby to these isoflavones has the potential to influence immediate and future reproductive development.  …EACs at levels of exposure that mimic those found in humans in North America produces target effects that indicate changes in cell function.”

EPA also confirms, “An ‘environmental endocrine disruptor’ has been defined as ‘an exogenous agent that interferes with the production, release, transport, metabolism, binding, action or elimination of natural hormones in the body responsible for the maintenance of homeostasis and the regulation of developmental processes.  In addition to the so-called ‘environmental estrogens’… the term includes agents that affect the thyroid and pituitary glands and other components of the endocrine system.” 

 EPA again confirms, “In our study, 50% of the 49 chemical compounds tested exhibited estrogenic activity in the two bioassays: …and phytoestrogens. Because the endocrine system plays a critical role in growth, development and reproduction, even small disturbances in endocrine function can have profound and lasting effects.  It is known that impacts of endocrine disturbances in humans or animals can be particularly damaging if exposure occurs during the highly sensitive prenatal.”

1996, and again the EPA confirms, “Phytoestrogens are naturally occurring non-steroidal plan chemicals with estrogen-mimetic properties.” 

1998, and again the EPA confirms, “Consideration should be given to ensuring that existing programs such as NHANES (National Health and Nutrition Survey) include monitoring of the important classes of EDC’s such as phthalates, phenols, (soy) phytoestrogens, organochlorines, and other pesticides and herbicides.”

2002, and the EPA sponsored workshop, called “Endocrine Disruptors Program Review Workshop” report by Claude Hughes et al also confirms, “For some of these endpoints, (soy) daidzein and genistein mimicked DES; however, unique or opposite responses were evident for each of the phytoestrogens including the low dose of genistein.”

Yet the EPA will not lawfully ensure American public disclosure of equal knowledge of the estrogenic activity in soy phytoestrogenic endocrine disruptors (whether transplacental or fed from soy infant formulas and foods), of which mimic DES, an established developmental poison, of which both DES and soy phytoestrogenic endocrine disruptors are never proven as neurologically fetal, infant, and child safe.

1990’s NIH soy researchers such as Drs. Doerge and Sheehan repeatedly warn, "Although safety testing of natural products, including soy products is not required, the possibility that widely consumed soy products may cause harm in the human population via either or both estrogenic and goitrogenic activities is of concern."  .

Several renowned NIH and FDA soy phyto-toxic researchers such as: Doerge, Sheehan, Newbold, Patisaul, Jefferson, Chang, Delclos, and countless others, have for several decades and to this day, continue to repeatedly study report that soybean phytoestrogenic endocrine disruptors, and/or additional soybean phyto-poisons are capable of causing severe and irreversible adverse developmental body and/or brain effects to once healthy fetus, infants, and children.  Absent heartedly, NEVER is there public disclosure.

Soy infant formulas and infant soy foods, as majority of soybean products contain GMO’s of which are again NOT proven as neurologically fetal, infant, or child safe. Proposition 65 recently includes this popular Monsanto soybean glyphosate herbicide on their list of carcinogens. 

Norway, 2013, T.Bohn et al report, “Compositional differences in soybeans on the market: Glyphosate accumulates in Roundup Ready GM soybean. …soybeans were planted on about 30 million hectares in the USA, with (Monsanto) Roundup Ready GM soy contributing 93-94% of the production.  However we argue that compositional studies that have overlooked (not measured) pesticide residues contain serious shortcomings.  Chemical residues… may add toxic properties to the final plant product either by itself or by affecting the plant metabolism.  This is particularly relevant for herbicide-tolerant varieties.  USDA data document dramatic increases in the use of glyphosate-based herbicides and GM soy is a major driver for this development.   A reduced body size of juveniles was even observed at exposure to Roundup….   …conclusion that the weight of evidence indicates that glyphosate itself is a teratogen and that adjuvants commonly used in conjunction with glyphosate amplify this effect.”

It is no secret that the USDA maintains a Monsanto “Revolving Door,” a loaded gun that targets all healthy American people.  And infant soy formulas contain soybean plant-poisons that are also saturated with GMO glyphosate.  All without evidence of developmental body- or brain-safety!

Again without public disclosure, soy isoflavone phytoestrogenic endocrine disruptors are study proven as increasingly poisonous in combination with:  1. A second endocrine disruptor: pesticides, plastics, lead, mold, water or air pollution, etc.,  2. Estrogenic and/or endocrine disruptor prescribed drugs. 

Soy is also reported as capable of disrupting the potency of some vaccines.  There are also three vaccines (Influenza-Afluria, Hib/Hep B-Comvax, and Pnemococcal-PCV13- Prevnar 13) that contain soy.  How dangerous to babies is this direct shot of soy phytoestrogenic endocrine disruptors, has never been investigated.

Is it legal that at the very same time that the HHS, NIH, and FDA refuse to post lawful "Warning" labels on developmental exposure to soy phyto-poisons, they withhold the fact that they continue to actively plan and organize an assortment of taxpayer multi-million dollar never-ending studies to investigate adverse soy phyto-poisonous developmental body and brain effects?   SEAD, SEED, IFED, EARLI, MARBLES, CHARGE, National Children's Study, Beginnings Study...and how many more? 

At the same time a million or more innocent and loving parents are unknowingly feeding their babies soy phyto-poisons because they trust the NIH and FDA, it is an outrageous undisclosed example of which the NIH NIEHS describes the SEAD soy study, "To establish methods for future larger studies on the estrogenic effects of soy infant formula on the developing infant." 

And frightfully sad,  the soy “Infant Feeding and Early Development” study (IFED) reports, “…looking for evidence of the infants’ response to the estrogen exposure from soy as well as other putative ‘endocrine disrupting’ chemicals.”  

Although heavily under the influence of Soy Industry/Pharma funding the "Beginnings Study" reports: "Nonetheless, questions remain regarding potential long-term adverse health effects of soy protein-based formula consumption due to the isoflavone content in the soy protein isolate used as the sole protein source in these formulas.  Soy isoflavones have been shown to interact with estrogen receptors and therefore could have an effect on the reproductive system and other hormone sensitive tissues including… development, adult fertility, hormonally sensitive cancers...and bone development."

In spite of the fact that the Arkansas Children's Nutritional Center and/or researchers working on the "Beginnings Study" are saturated in soy interest funding, they report soy formulas are, "...some reasons to be 'concerned' about possible drawbacks of soy proteins."

Too often developmental soy phyto-toxic studies, involve soy industry, and/or Pharmaceutical, or Monsanto interests: funding, consulting, contracts, grants, review, etc.    Tragically, ongoing U.S. Health Organization soy phyto-poisonous studies, funding, and results are NOT  publicly disclosed while millions of American babies are fed soy phyto-poisonous infant formulas, or soy contaminated infant “milk” formulas and foods.

With decades of existing mass study evidence that describes the soy phyto-poisonous cause of developmental body, brain, behavioral disorders to include autism, there are NO parental health questionnaires that justifiably question the child’s history of exposure to soy phytoestrogenic endocrine disruptors plus additional soy phyto-poisons of health-damaged children. Why not? 

NO Developmental Soy Infant Formula Phyto-Poisonous BENEFIT:
To date, the ONE soy infant formula benefit was as a replacement for lactose intolerance or milk allergies of which had become obsolete.  Soybeans are high level allergens.  To date, “Lactose-free” infant formulas are in truth beneficial: safe and nutritional.  Soy phytoestrogenic endocrine disruptors plus additional soy phyto-poisonous infant formulas remain popularly U.S. marketed… without benefit, and without evidence that any normal infant is able to body- and/or brain-survive. This is reason why soy infant formulas are forbidden for pre-term babies…no safety, no nutritional value!  It is once healthy American babies who become prey, placed directly into the path of unnecessary adverse body- and brain-effects to suffer from for a lifetime.

Soybeans encourage dangerous peanut allergy reactions!  Asthma and Allergy Resource Center reports, "Soy induced anaphylaxis in children with asthma and peanut allergy.  What you may not know is that infants and children with peanut allergies can have an allergic reaction after eating a food that contains soy..."

Allergy Kids Foundation confirms, "Ten years ago, in 1996 soy was genetically engineered with chemical toxins to make it a more profitable crop.  That same year, there was a 50% increase in soy allergy...”

“Codex Alimentarius” (book of food) contains food health standards set by the World Health Organization and the Food And Agriculture Organization of the United Nations that are to be respected by the USA.  The Codex Alimentarius contains strict safety requirements for infant formulas, "All ingredients shall be...of good quality, safe and suitable for ingestion by infants…and shall not contain any other poisonous or deleterious substances in amounts which may represent a hazard to health."

As no other country in the world, the USA popularly and inconspicuously markets soy infant formulas, soy contaminated infant “milk” formulas and foods on grocer shelves without fair or law-abiding “Warning” labels.  Of no coincidence, powerful multi-billion dollar soybean industries, Pharmaceuticals marketing soy infant formulas, and Monsanto GMO soy profiteers are also located in the USA.

I doubt if even George Washington understood the true depth of his statement, “Few men have virtue to withstand the highest bidder.”


As previously stated, researchers Patisaul and NIEHS W. Jefferson conclude, “Internationally the use of soy formula is viewed more cautiously than in the U.S."

Unlike the USA, home to a powerful army of multi-billion dollar corporate soybean profiteers, Italy, France, Israel, New Zealand, Switzerland, Denmark, Germany, Canada, UK, India, Korea, (and how many more countries?), all prioritize their promised oath to responsibly first, and foremost protect baby-health,  while refusing to market soy infant formula and foods on grocer shelves.

2002, UK Scientific Advisory Committee on Nutrition, (SACN) reports, "There is cause for concern about the use of soy-based infant formulaThere is neither substantive need for soy-based infant formulae nor health benefit arising from their use."

2006, New Zealand, renowned soy researcher Dr. Michael Fitzpatrick published several adverse health soy studies, and he wrote letters to the FDA and CFSAN requesting public disclosure of soy-phyto-toxicity. His requests are denied.  Dr. Fitzpatrick wrote, “...much research into the effects of isoflavones has shown quite conclusively their reproductive toxicity to a large range of animals.  These included rats, mice, pigs, cheetah, quail and fish.  It is well established that the soy-isoflavones can modify the menstrual cycle of human females at moderately low doses.  I am involved with current research that shows that similarly low doses to adult male humans reduces testosterone levels....  I am particularly 'concerned' about the very high doses of isoflavones that infants fed soy-infant formula receive and understand this very issue is being closely followed by the EPA."

National Institute of Toxicological Research in Seoul, Korea, researchers SJ Kwach et al, report: "Risk Assessment of Soybean-Based Phytoestrogens.  However, phytoestrogens are considered to be potential endocrine-disrupting chemicals (EDC), which interfere with the normal function of the hormonal and reproductive systems. Therefore, dietary exposure to soybean-based phytoestrogens is of 'concern' for Koreans....  These results suggest that dietary exposure to phytoestrogens, such as daidzein and genistein, poses a relatively higher health risk for humans than synthetic EDC."

2005, French Food Safety Agency, "The consumption of phytoestrogens cannot a priori be considered safe, because they interfere with the hormonal system, and as such merit examination.  For infant and young children taking soy-protein based formula, it is recommended that phytoestrogen intake be limited....   In the same way, in utero and neonatal exposure needs to be limited.  …as has been shown in children, phytoestrogen consumption can increase thyroid hormone requirements in patients being treated for hypothyroidism."

2006 French (Pubmed) study reports, "Phytoestrogens and soy foods in infants and children: caution is needed."

German study reports, "Soy and infants--that is incompatible.  Plant proteins are no substitute for normal milk products / adverse effects possible."  Kinderkrankenschwester. 2008 Jul;27(7):286.

Additional Study Reported Soy Phyto-Poisonous Risks Caused to Exposed Children Without U.S. Health Disclosure:
As all parents’ nightmare, throughout prior decades and to this day, there are nearly a thousand NIH Pubmed published studies that repeatedly and increasingly conclude fetal, infant, and/or child exposure to soybean phytoestrogenic endocrine disruptors plus additional developmental soy phyto-poisons have potential to cause multiple childhood diseases and disorders to include: leukemia, pancreatic cancer, a variety of cancers, cancer metastasis, severe thyroid dysfunction or disease, immune deficiency diseases, diabetes, inferior growth and development, allergies, asthma, anaphylaxis, multiple reproductive diseases and disorders, (to include male or female infertility in adulthood), cardiovascular disease, obesity, gastrointestinal distress, gender chaos, hypospadias, homosexuality, (demasculinization/feminization of males,  defeminization/masculinization of females), seizures, and multiple neurological and behavioral disorders that includes autism 

Another U.S. epidemic is childhood obesity that can be caused not only by poor dietary habits, and/or no exercise, but soy phytoestrogen-caused.  According to the Environmental Health Perspectives of the NIH NIEHS, “Obesity is strongly linked with exposure to risk factors during fetal and infant development.  Certain pharmaceuticals…have been linked to weight gain …as have a handful of dietary obesogens, including the soy phytoestrogen genistein….   Most known or suspected obesogens are endocrine disruptors.” 

Again without public disclosure, soybean phyto-poisons are dietary obesogens, or the cause of obesity!

Worthy of, but sorely lacking representation from multiple U.S. Food and Health Laws that protect American children’s health, innumerable soybean plant-poisons are NEVER proven as fetal, infant, or child physiologically, reproductive, or neurologically safe!

The math fits:  Increase in popular U.S. marketing of omnipresent soy phyto-poisons contaminate fetus, infants, and children  +  Increase in U.S. diagnoses of severe and irreversible infant and child diseases and brain disorders to include Autism  =  Not coincidence; but the soy phytoestrogenic endocrine disruptor plus additional soy phyto-poisonous CAUSE of multiple adverse developmental body and brain effects. 

1.  Boys:
* Estrogens are important for the development and maintenance of brain function.  NIH Pubmed studies overwhelmingly conclude- soybean phytoestrogenic endocrine disruptors plus additional soy phyto-poisons are able to permanently derail, disrupt, rearrange, and damage several developing brain neurotransmitter systems and brain circuitry in females, and cause even greater adverse neuronal damage in males.  Soy phytoestrogenic hormone disruptors cause the dangerous imbalance between critical testosterone to estrogen hormone ratio levels.  This fact coincides with the higher rate of autism diagnosed in boys. 

2.  Multiple Children in One Family:
* Without law abiding public "Warning" labels, and while misled of developmental health and safety, families continue to unknowingly swallow soy phyto-poisonous products.  This fact coincides with the probability of more than one autistic child in a family.

3.  Autistic Children Commonly Suffer From Multiple Diseases/Disorders:
* Brain and body hormone systems are harmoniously connected.  Most often autistic children suffer from multiple disorders or diseases.  NIH Pubmed studies repeatedly confirm soy phyto-poisons cause multiple developmental adverse physiological, reproductive, and/or neurological effects.  Particularly diagnosed in autistic children are gastrointestinal disorders, epilepsy, and seizures.  Published studies repeatedly confirm the soy phyto-poisonous cause of these precise adverse effects seen in autistic children!

SOY Phyto-Poisons Are Proven To Force Medical Treatments That Force Medical Cost Hardships!

2015, Renowned researchers Dr. Leonardo Trasande and his team report, “Context: Rapidly increasing evidence has documented that endocrine-disrupting chemicals (EDCs) contribute substantially to disease and disability.  Expert panels achieved consensus at least for probable (>20%) EDC causation for IQ loss and associated intellectual disability, autism, attention-deficit hyperactivity disorder, childhood obesity, adult obesity, adult diabetes, cryptorchidism, male infertility, and mortality associated with reduced testosterone.  Conclusions:  EDC exposures... are likely to contribute substantially to disease and dysfunction across the life course with costs in the hundreds of billions... per year.”

I asked Dr. Trasande, "Does your research on endocrine disrupting chemicals that contribute substantially to disease and dysfunction with your found resulting medical costs include exposure to soy phytoestrogenic endocrine disruptors? 

Dr. Leonardo Trasande answered the affirmative, "Our analyses accounted for potential health effects of naturally occurring endocrine active chemicals, including the ones you described....  We estimated the cost of health effects... and whose exposure could be reduced through regulatory activity." 

NIH NIEHS Director Birnbaum confirms, “…environmentally linked diseases… can affect an individual’s entire life, with potentially large impacts on both quality of life and health care costs.”

Although withheld from public disclosure, soybean phyto-poisons are overwhelmingly study established as environmental poisons that cause any host of diseases and disorders particularly in most vulnerable exposed fetus, infants, and children.  Where is lawful public disclosure?

PLEASE do not use and abuse the sorely faulty NTP CERHR Panel “Opinion” as IACC SCAPEGOAT-

Why would unprofessionally, bogus, and brief 2006 and 2009 NTP CERHR soy infant formula meetings of which a small non-expert panel “Opinion” unfairly and unfaithfully trump multiple U.S. Health Official testimonies, and nearly a thousand in-depth and highly respected scientific soy phyto-poisonous developmental studies all concluding adverse developmental effects?

After the 2006, NTP CERHR Brief on Soy Infant Formula- Highly renowned soy researcher Dr. Kenneth Setchell wrote to CFSAN Director Michael Shelby, “So we are left pondering what all these animal experiments mean.  To deny that soy isoflavones have biological effects would be absurd given a wealth of evidence from in vitro, cellular, and molecular studies.”

Responding to the 2006 NTP CERHR Brief on Soy Infant Formula, Doctor Lindy Woodard wrote to NIH CERHR Director Shelby"I am deeply concerned about the expert panel's conclusion....  Over the years, expert independent scientists including leading toxicologists from the FDA's and NIEHS's own laboratories have expressed serious concerns about the effect of soy phytoestrogens on brain, thyroid, and reproductive development.  We need to take their conclusions seriously.  The U.S. should follow examples of the Israeli Health Ministry and British Dietetic Association who warn parents and pediatricians about the potential dangers of soy infant formula.  I personally know of the dangers of soy infant formula because I have been practicing pediatrics for 30 years and observed for myself that babies are not healthy on soy formula.  I hope that this letter will encourage the panel to reconsider its conclusions and to commit to precautionary principle of 'better safe than sorry."

And PLEASE do not use and abuse the scapegoat of the December 2009 NTP CERHR review of soy infant formula.  I was there, and it is my testimony that the vast majority of the 14 member panelists were NOT in the least soy experts, but most frightfully the majority being largely under the influence of direct and/or indirect soybean interest funding.  From the start, a large number of panelists were obviously pro-soy biased and pleasing to multiple soy funded lobbyists in the room. 11 non-expert panel members voting their simple “OPINION” of “minimal concern” in spite of many times concluding “Clear Evidence of Adverse (soy) Effects.”  The higher soy-funded influence, Jatinder Bhatia, was the one panelist to vote the impossible, “negligible concern.”  

February, 2010, Judith Palfrey the President of American Academy of Pediatrics states,  "Jatinder Bhatia,… recused himself from the review of this document and development of comments....  Concerns have been raised in relation to the safety of phytoestrogens and isoflavones, including their potential negative effects on sexual developmental and reproduction, neurobehavioral development, immune function, and thyroid function.  AAP appreciates that the CERHR has revisited the potential developmental and reproductive toxicities of soy infant formulaSince the first panel convened in 2006, a number of new studies have been published related to human exposure, reproductive toxicity, and developmental toxicity for soy infant formula."

“Concerns,” there are massive numbers of professionally voiced legitimate “Concerns” over developmental soy phytoestrogenic endocrine disruptor plus additional soy phyto-poisons that contaminate fetus, infants, and children as can also be common sense expected.  Where is public disclosure?

Against NTP CERHR guidelines the 2009 panel refused to review multiple adverse developmental soy studies placed on their desks.  Also, importantly, this NTP CERHR meeting was stated for exclusive review of soy phyto-poisonous-cause of adverse developmental reproductive health… of which was ridiculously reviewed on soy-exposed babies, instead of reproductive age.  This NTP CERHR panel was also instructed to review evidence of soy phytoestrogenic endocrine disruptors plus additional soy phyto-poisons exclusively on baby reproduction, and NOT for adverse physiological or neurological effects.  Although the panel reports, “Clear Evidence of Adverse Effects” their 11 biased votes were the impossible “minimal concern.”  

Therefore, please do not use the bogus, non-expert NTP CERHR Brief, very brief soy infant formula meeting consisting of 11 non-expert “opinions” as your scapegoat. 

The 2006 Combating Autism Act (CAA) confirms, "Federal declaration of war on the epidemic of autism.  An information and education program and its risk factors to be provided by the HHS to health professionals and the general public." 

As you know, CAA and CARES (Collaboration, Accountability, Research, Education and Support) Acts read,  “Recent studies supported by NIH have uncovered distinct differences in the brain development of infants who later are diagnosed with ASD, while studies supported by NIH, DoD and EPA have identified potential contributions to ASD risk from diverse environmental risk factors including nutrients, air pollutants, pesticides and paternal age.”  

“Soy Infant Formula” phytoestrogenic endocrine disruptors are NIH NIEHS established environmental risk factors!  Multiple U.S. Health Officials and Health Organizations all concur with the massive evidence confirming the soy phyto-poisonous cause of adverse developmental health.  This acknowledgement deserves equal public knowledge that can result in the protection of developmental physiological, reproductive, and neurological health. 

As your appointed duty, the IACC Committee is aware of established autism laws that require autism research; whether possible, probable, or absolute in the evidence that details a cause of autism, is to be unquestionably allowed as public information. 

Therefore, this is an urgent request that you allow mass evidence that clearly documents the fetal, infant, and/or child developmental exposure to fluctuating levels of soy phytoestrogenic endocrine disruptors plus additional soy phyto-poisons that are placed into soy infant formulas, soy added infant “milk” formulas and foods are physiological, reproductive, and neurological poisons that cause behavioral disorders to include autism, until proven as brain-safe.

As established, NIH NIEHS Director Birnbaum confirms,  “…it is apparent that endocrine disruption is an important emerging public health concern.”

As critically important right-to-know public information; fetal, infant, and/or child exposure to unknown fluctuating dosage levels of the several soybean phytoestrogenic endocrine disruptors, plus additional soybean phyto-poisons have never been proven as physiologically, reproductive, or neurologically safe, while overwhelming evidence concludes the cause of a host of severe and irreversible adverse developmental body- and brain-effects that are wrongfully, negligently, and unlawfully withheld from trusting American public disclosure.     

Executive Order 13045- “Protection of Children From Environmental Health Risks and Safety Risks" lawfully requires: Section 1. Policy- 1-101- A growing body of scientific knowledge demonstrates that children may suffer disproportionately from environmental health risks and safety risks.  These risks arise because: children's neurological, immunological, digestive, and other bodily systems are still developing....  Each Federal agency: (a) shall make it a high priority to identify and assess environmental health risks and safety risks that may disproportionately affect children; and (b) shall ensure that its policies, program, activities, and standards address disproportionate risks to children that result from environmental health risks or safety risks.  1-102. Each independent regulatory agency is encouraged to participate in the implementation of this order and comply with its provisions.  2-203- 'Environmental health risks and safety risks' mean risks to health or to safety that are attributable to products or substances that the child is likely to come in contact with or ingest (such as the air we breath, the food we eat, the water we drink or use for recreation, the soil we live on, and the products we use or are exposed to)."

Catastrophic Bottom Line-  Innumerable American parents are left ignorant to the potential of soy-poisoning of their own babies, while there remain NO lawful U.S. “Warning” labels as an equal opportunity for an innocent American public to protect their babies’ health.  All the while without lawful parental disclosure, a million or more American babies are repeatedly fed soy phyto-poisonous formulas, thus participating in an undisclosed and undocumented game of developmental adverse body- and brain-roulette.  None of the HHS, NIH, or FDA studies have ever established developmental soy phyto-poisoning body- or brain-safety!

In Conclusion:

EPA Office of Children’s Health states, “American children have the right to a healthy and safe future…”

In accordance with the above enclosed  information, “Soy Infant Formula” (and soy contaminated infant "milk" formulas and foods) are a highly toxic confirmed NIH NIEHS “Environmental Agent,” of which soy phytoestrogenic endocrine disruptor plus additional soy phyto-poisons are time and time again established as fetal, infant, and child neural-poisons, with brain-toxic probability to cause irreversible neurodevelopmental disorders, to include autism, of which requires life-long medical treatments and medical cost hardships. 

As you well know, autism is a developmental health crisis reaching epidemic proportions.  Autism is a life-long neurological disorder that may very well be prevented with law-abiding public knowledge of this mass evidence concluding soy phytoestrogenic endocrine disruptors plus additional soy phyto-poisons as a cause, while never proven as neurodevelopmentally safe.  Autism steals the brain from American children who grow into the future of a large population of struggling American adults, of which even the slightest potential risk must be righteously and lawfully revealed as critical public health information.  Here in your hands, you have the power to save the life-long neurological well-being of our most treasured population.

Frightfully unfair, the untold public health enigma remains: Will any particular fetus, infant, or child be able to normally body- and/or brain-survive developmental exposure to fluctuating levels of soy phytoestrogenic hormone disruptors plus several additional soy phyto-poisons?

Therefore, this is a truly valid request that you, the IACC Committee appointed to protect fetal, infant, and child brain-health will dutifully enforce law-abiding public disclosure “Warning” labels on soy infant formulas and foods, until the many soybean containing phyto-poisons can ever be proven as developmentally brain-safe. 

I am most hopeful that while without evidence of fetal, infant, and child neurological survival, you will agree that IACC Committee acknowledgement of adverse fluctuating dosage levels of soy phytoestrogenic endocrine disruptors plus multiple additional soybean phyto-poisons, of which are repeatedly and increasingly concluded as developmental neurotoxicants, unquestionably warrants your urgent law-abiding public disclosure to protect a large American population from a lifetime of neurological disorders such as autism.

I very much appreciate your time, and will look forward to your reply.

G.A. Elbek- Investigative researcher
Santa Barbara, CA

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